Antibacterial photodynamic therapy

Repeated Daily Use of Dual-Light Antibacterial Photodynamic Therapy in Periodontal Disease—A Case Report

https://www.mdpi.com/2304-6767/10/9/163

Trujiilo, K.; Räisänen, I.T.; Sorsa, T.; Pätilä, T. Repeated Daily Use of Dual-Light Antibacterial Photodynamic Therapy in Periodontal Disease—A Case Report. Dent. J. 2022, 10, 163. https://doi.org/10.3390/dj10090163

 

Good oral hygiene at home is the foundation for optimal treatment response and long-term periodontal disease control. Antibacterial photodynamic therapy (aPDT) provides a potent adjunctive treatment for plaque control. However, literature regarding repeated aPDT use has been so far sparse. A new case study presents very positive results and clinical outcome of daily applied dual-light aPDT-technology treatment in conjunction with mechanical cleaning of a 78-year-old male patient with severe periodontal disease (Stage IV and Grade B).

The case report describes a periodontitis patient with difficulties maintaining mechanical oral hygiene. The patient received continuous aPDT treatment for 6–7 months, using the device every other day. The ability of the patient to keep his periodontal pockets infection-free indeed improved and enhanced after the device use. The number of deep periodontal pockets reduced from two 7 mm pockets to zero, and the number of moderately deep periodontal pockets reduced from 43 to 1. At the same time, the clinical attachment level improved significantly during the treatment.

According to the study, the most important difference to the existing aPDT treatments in Lumoral use is the consistency of the treatment application. In most publications to date, the aPDT is reported to be given only once. Lumoral enables continuous use.

The Lumoral device is able to provide aPDT for supragingival plaque, but also through the periodontal tissue into the periodontal pocket, a method called transgingival light application, the study shows. The product is used in combination with an oral rinse, Lumorinse, which is packaged in tablet form.

The recovery from an unstable Stage IV periodontal disease during the 13-month surveillance period was excellent, the study reveals. There was a clear improvement in oral hygiene and a significant reduction in infected pockets. In addition, the clinical attachment level improved. There was only one residual infected periodontal pocket left, and the etiology of this residual pocket can be argued to be at least partly due to occlusion trauma, authors note.

However, as the results are based on a case study, generalization of the results to a wider population is not possible, authors add. Nevertheless, the excellent results from this case report study support conducting further studies in different, larger populations with various cases of periodontal conditions.

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